Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650892 | 0.87 | MAOA (0.35) | TRPA1 | |
| Water SCHEMBL10588716 | 0.86 | MAOA (0.34) | — | |
| SCHEMBL6670016 | 0.77 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL6668777 | 0.74 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL6667856 | 0.74 | TRPA1 (0.36) | TRPA1 | |
| Arginine SCHEMBL6240955 | 0.73 | OTC (0.32) | — | |
| SCHEMBL9426990 | 0.70 | LMNA (0.30) | — | |
| SCHEMBL7258261 | 0.69 | PARP1 (0.36) | — | |
| SCHEMBL4509562 | 0.66 | CA1 (0.31) | — | |
| SCHEMBL11296259 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494978-A1 | HETEROCYCLIC COMPOUNDS. | WYETH JOHN & BROTHER LTD (GB) | 1992-07-22 | — | — | EP | claimed |
| WO-1991005783-A1 | HETEROCYCLIC COMPOUNDS | JOHN WYETH & BROTHER LIMITED (GB) | 1991-05-02 | — | — | WO | claimed |
| US-5096901-A | PHARMACOLOGICALLY ACTIVE AMIDES AND ESTERS CONTAINING AN AZABICYCLOALKANE MOIETY | JOHN WYETH & BROTHER LIMITED (GB) | 1992-03-17 | — | — | US | disclosed |