Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 11/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27265721 | 0.72 | L3MBTL1 (0.40) | TSHRTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL8330923 | 0.71 | SMN1; SMN2 (0.54) | NAAACYP1A2CYP2C19SMN1; SMN2TSHR | |
| SCHEMBL7923337 | 0.71 | ADRA2A (0.53) | NAAATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL31188973 | 0.68 | ALDH1A1 (0.45) | CYP1A2CYP2C19SMN1; SMN2TSHRTDP1 | |
| SCHEMBL9875528 | 0.68 | TAOK1 (0.44) | NAAACYP1A2CYP2C19SMN1; SMN2TSHR | |
| SCHEMBL10446636 | 0.67 | EPHX2 (0.49) | L3MBTL1 | |
| SCHEMBL4611129 | 0.67 | NAAA (0.41) | NAAACYP1A2CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL12606479 | 0.66 | NAAA (0.52) | NAAASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL30890494 | 0.66 | TSHR (0.44) | CYP1A2CYP2C19SMN1; SMN2TSHRTDP1 | |
| SCHEMBL7365192 | 0.66 | TSHR (0.41) | TSHRTDP1L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106861-A | Method of using certain tetralin derivatives to produce analgesic relief | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-21 | — | — | US | disclosed |