Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449173 | 0.81 | ALDH1A1 (0.44) | L3MBTL1TSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL9449258 | 0.80 | CNR1 (0.47) | L3MBTL1TSHRSQORPPARGGHSR | |
| SCHEMBL9846076 | 0.72 | MAPT (0.44) | LMNAHTTKDM4ENPC1TP53 | |
| SCHEMBL15814133 | 0.71 | TSHR (0.45) | L3MBTL1TSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL4510054 | 0.70 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MAPK1HTTKDM4E | |
| SCHEMBL15584082 | 0.69 | PPARG (0.49) | L3MBTL1TSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL16616128 | 0.69 | MCL1 (0.50) | L3MBTL1TSHRPPARG | |
| Alcohol SCHEMBL9721767 | 0.68 | TSHR (0.75) | L3MBTL1TSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL31230219 | 0.68 | L3MBTL1 (0.46) | L3MBTL1TSHRALDH1A1LMNAMAPK1 | |
| SCHEMBL2674878 | 0.68 | L3MBTL1 (0.50) | L3MBTL1TSHRALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |