Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545178 | 0.79 | HSD11B1 (0.42) | MAPTKMT2ASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL8413935 | 0.78 | ALDH1A1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8029164 | 0.77 | ALDH1A1 (0.50) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL2331407 | 0.74 | NR4A2 (0.52) | KEAP1NR4A2MAPTMEN1KMT2A | |
| SCHEMBL1720891 | 0.73 | ALDH1A1 (0.41) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| Azobenzene SCHEMBL32679252 | 0.73 | MAPT (0.69) | KEAP1NR4A2MAPTMEN1KMT2A | |
| SCHEMBL7162802 | 0.71 | NR4A2 (0.48) | KEAP1NR4A2MAPTMEN1KMT2A | |
| SCHEMBL10502034 | 0.70 | ALDH1A1 (0.38) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL8851294 | 0.70 | KEAP1 (0.54) | KEAP1NR4A2MAPTFFAR1HDAC3 | |
| SCHEMBL1720603 | 0.70 | POLB (0.42) | KEAP1MAPTSMN1; SMN2ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476760-A2 | 4-substituted isoxazole herbicides | EASTMAN KODAK COMPANY (US) | 1992-03-25 | — | — | EP | claimed |
| EP-0476761-A1 | 4-substituted isoxazoles | EASTMAN KODAK COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |