SCHEMBL9681049

SCHEMBL9681049

CC(C)(C(=O)c1ccccc1)N1CCNCC1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.54
ALDH1A1 P00352 2/20 0.49
TSHR P16473 2/20 0.49
USP2 O75604 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
OPRD1 P41143 5/20 0.43
HPGD P15428 1/20 0.43
POLB P06746 1/20 0.41
CES1 P23141 1/20 0.41
KMT2A Q03164 1/20 0.41
HTR6 P50406 1/20 0.40
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
ADRB1 P08588 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10943745 0.94 SIGMAR1 (0.49) SIGMAR1ALDH1A1TSHRUSP2HSD17B10
SCHEMBL10943325 0.94 ALDH1A1 (0.59) SIGMAR1ALDH1A1TSHRUSP2HSD17B10
SCHEMBL9679437 0.87 ALDH1A1 (0.50) SIGMAR1ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL10943751 0.86 ALDH1A1 (0.49) SIGMAR1ALDH1A1TSHRUSP2HSD17B10
SCHEMBL27904024 0.85 SIGMAR1 (0.50) SIGMAR1ALDH1A1TSHRUSP2HSD17B10
SCHEMBL3007482 0.84 HPGD (0.48) ALDH1A1TSHRUSP2HSD17B10MAPK1
SCHEMBL11896665 0.82 ALDH1A1 (0.46) SIGMAR1ALDH1A1TSHRUSP2HSD17B10
SCHEMBL9680403 0.82 HPGD (0.52) ALDH1A1TSHRUSP2HSD17B10MAPK1
SCHEMBL2703637 0.82 ALDH1A1 (0.56) SIGMAR1ALDH1A1TSHRUSP2HSD17B10
SCHEMBL9681216 0.81 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163017-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME NIMMUNE BIOPHARMA, INC. (US) 2025-05-22 US disclosed
US-12145920-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same NIMMUNE BIOPHARMA, INC. (US) 2024-11-19 US disclosed
EP-3927427-B1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME NIMMUNE BIOPHARMA INC (US) 2024-02-07 EP disclosed
CN-113748109-B Lanthionine C-like protein 2 ligands, cells prepared with said ligands and therapies using said ligands 朗多生物制药股份有限公司 2023-07-21 CN disclosed
US-20220274950-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2022-09-01 US disclosed
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2022-07-05 US disclosed
EP-3927427-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-12-29 EP disclosed
CN-113748109-A Lanthionine C-like protein 2 ligands, cells prepared with said ligands and therapies using said ligands 朗多生物制药股份有限公司 2021-12-03 CN disclosed
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LANDOS BIOPHARMA, INC. (US) 2021-11-18 US disclosed
US-11117881-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LANDOS BIOPHARMA, INC. (US) 2021-09-14 US disclosed
US-20070160921-A1 Electrophotographic photoconductor, method of producing the same and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2007-07-12 US disclosed
US-20070160921-A1 Electrophotographic photoconductor, method of producing the same and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2007-07-12 US disclosed
US-5145885-A Morpholine compound, binders CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
US-4992547-A Aminoaryl ketone photoinitiators CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
US-4960746-A A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE CIBA-GEIGY CORPORATION (US) 1990-10-02 US disclosed
EP-0003002-B1 USE OF AROMATIC-ALIPHATIC KETONES AS PHOTOINITIATORS, PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH KETONES AND AROMATIC-ALIPHATIC KETONES CIBA-GEIGY AG (CH) 1984-06-13 EP disclosed
US-4321118-A Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition CIBA-GEIGY CORPORATION (US) 1982-03-23 US disclosed
US-4318791-A PHOTOPOLYMERIZABLE SYSTEM FOR INKS CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4315807-A Sensitizers for photopolymerization CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4308400-A AROMATIC HYDROXY KETONES CIBA-GEIGY A.G. (CH) 1981-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163017-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB SIGMAR1 3734/4885ALDH1A1 4546/4885TSHR 1609/4885
US-11377437-B2 Lanthionine C-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB SIGMAR1 3734/4885ALDH1A1 4546/4885TSHR 1609/4885
US-20210355101-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB SIGMAR1 3734/4885ALDH1A1 4546/4885TSHR 1609/4885
US-12145920-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB SIGMAR1 3734/4885ALDH1A1 4546/4885TSHR 1609/4885
US-11117881-B2 Lanthionine c-like protein 2 ligands, cells prepared therewith, and therapies using same LCP2, LANCL2, SSB SIGMAR1 3734/4885ALDH1A1 4546/4885TSHR 1609/4885
US-20220274950-A1 LANTHIONINE C-LIKE PROTEIN 2 LIGANDS, CELLS PREPARED THEREWITH, AND THERAPIES USING SAME LCP2, LANCL2, SSB SIGMAR1 3734/4885ALDH1A1 4546/4885TSHR 1609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.