Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943325 | 0.94 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10USP2SMN1; SMN2 | |
| SCHEMBL9681049 | 0.86 | SIGMAR1 (0.54) | ALDH1A1TSHRHSD17B10USP2SMN1; SMN2 | |
| SCHEMBL2703637 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10USP2SMN1; SMN2 | |
| SCHEMBL10384362 | 0.84 | HTR3E (0.49) | ALDH1A1TSHRHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL10943745 | 0.84 | SIGMAR1 (0.49) | ALDH1A1TSHRHSD17B10USP2SMN1; SMN2 | |
| SCHEMBL9681216 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL2704635 | 0.84 | ALDH1A1 (0.69) | ALDH1A1TSHRHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL10943847 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL11896664 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10USP2SMN1; SMN2 | |
| SCHEMBL10941271 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1TSHRSMN1; SMN2MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |