Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679422 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL10943751 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9681282 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9679558 | 0.82 | SMN1; SMN2 (0.65) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9681049 | 0.81 | SIGMAR1 (0.54) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL2703637 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL10943325 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL2704635 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPTHPGDTSHRSMN1; SMN2 | |
| SCHEMBL10384362 | 0.79 | HTR3E (0.49) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL10943745 | 0.79 | SIGMAR1 (0.49) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |