Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187780 | 0.95 | HPGD (0.61) | NPC1HPGDRAB9ACRHBPCRHR2 | |
| SCHEMBL9681015 | 0.86 | NPSR1 (0.58) | NPC1HPGDRAB9ACRHBPCRHR2 | |
| SCHEMBL7565510 | 0.86 | RAB9A (0.71) | NPC1HPGDRAB9ACRHBPCRHR2 | |
| SCHEMBL11079563 | 0.85 | RAB9A (0.71) | NPC1HPGDRAB9ACRHBPCRHR2 | |
| SCHEMBL11135046 | 0.83 | RAB9A (0.50) | NPC1HPGDRAB9ACRHBPCRHR2 | |
| SCHEMBL5865879 | 0.81 | SMN1; SMN2 (0.67) | NPC1HPGDRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11444456 | 0.81 | RAB9A (0.48) | NPC1HPGDRAB9ACRHBPCRHR2 | |
| SCHEMBL7565512 | 0.80 | RAB9A (0.70) | NPC1HPGDRAB9ACRHBPCRHR2 | |
| SCHEMBL9146676 | 0.80 | LMNA (0.68) | NPC1HPGDRAB9ACRHBPCRHR2 | |
| SCHEMBL11790359 | 0.80 | RAB9A (0.65) | NPC1HPGDRAB9ACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136013-A | Polyesters | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| US-5068300-A | BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |