Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | CRHBP | P24387 | 1/20 | 0.71 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Phenylcarbamate SCHEMBL264865 | 0.89 | RAB9A (0.75) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| Ethyl Phenylcarbamate SCHEMBL11593824 | 0.89 | RAB9A (0.75) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| Ethyl Phenylcarbamate SCHEMBL10645999 | 0.87 | RAB9A (0.73) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| Ethyl Phenylcarbamate SCHEMBL27486650 | 0.87 | RAB9A (0.73) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL7565510 | 0.87 | RAB9A (0.71) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL9721920 | 0.87 | LMNA (0.62) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL9482116 | 0.86 | MAPT (0.79) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL5425007 | 0.86 | NPC1 (0.55) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL7565512 | 0.85 | RAB9A (0.70) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL9681078 | 0.85 | NPC1 (0.56) | RAB9ANPC1HPGDCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107073294-A | Methods of treating aging and skin conditions using nucleic acids targeting TYR or MMP1 | 阿克赛医药公司 | 2017-08-18 | — | — | CN | disclosed |
| US-4487713-A | HEAT TREATMENT WITH TITANIUM, TIN, ANTIMONY OR ZIRCONIUM COMPOUND | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-12-11 | — | — | US | disclosed |
| US-4081472-A | CATALYTIC, FROM A CARBAMATE | MITSUI TOATSU CHEMICALS INC. (JA) | 1978-03-28 | — | — | US | disclosed |
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | disclosed |