Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680731 | 0.88 | ALDH1A1 (0.44) | KMT2AMAPTMEN1SMN1; SMN2HTT | |
| SCHEMBL9681845 | 0.86 | MAPT (0.49) | KMT2AMAPTMEN1HTTALDH1A1 | |
| SCHEMBL9681063 | 0.85 | KDM4E (0.51) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9682456 | 0.84 | SMN1; SMN2 (0.56) | KMT2AMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9682440 | 0.83 | ALDH1A1 (0.54) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10786832 | 0.81 | ALDH1A1 (0.56) | KMT2AMAPTMEN1ALDH1A1TDP1 | |
| SCHEMBL9681882 | 0.81 | KMT2A (0.57) | KMT2AMAPTMEN1ALDH1A1TDP1 | |
| SCHEMBL2048011 | 0.79 | ALDH1A1 (0.58) | KMT2AMAPTMEN1ALDH1A1TDP1 | |
| SCHEMBL9001094 | 0.79 | ALDH1A1 (0.59) | KMT2AMEN1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9681115 | 0.78 | MAPT (0.45) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | claimed |