SCHEMBL9681063

SCHEMBL9681063

O=C(Oc1ccc(C(=O)OC(=O)c2ccc(OC(=O)c3cccc(Cl)c3)cc2C(=O)O)c(C(=O)O)c1)c1cccc(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 2/20 0.51
USP2 O75604 1/20 0.51
ALOX15 P16050 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
PYGL P06737 1/20 0.50
PYGM P11217 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
KMT2A Q03164 6/20 0.48
MEN1 O00255 3/20 0.48
MAPT P10636 2/20 0.48
NPC1 O15118 1/20 0.48
MITF O75030 1/20 0.48
PKM P14618 1/20 0.48
MAPK1 P28482 1/20 0.48
RAB9A P51151 1/20 0.48
MCL1 Q07820 1/20 0.48
ATM Q13315 1/20 0.48
AKR1C3 P42330 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9680731 0.87 ALDH1A1 (0.44) KDM4EALDH1A1NPSR1PYGLPYGM
SCHEMBL9681098 0.85 KMT2A (0.49) ALDH1A1ALOX15NPSR1KMT2AMEN1
SCHEMBL9680701 0.84 KMT2A (0.48) ALDH1A1KMT2AMEN1MAPTNPC1
SCHEMBL28132328 0.82 POLB (0.55) KDM4EALDH1A1PYGLPYGMKMT2A
SCHEMBL9681845 0.82 MAPT (0.49) KDM4EALDH1A1KMT2AMEN1MAPT
SCHEMBL9682456 0.81 SMN1; SMN2 (0.56) ALDH1A1ALOX15KMT2AMAPTNPC1
SCHEMBL9681115 0.81 MAPT (0.45) KDM4EALDH1A1PYGLPYGMKMT2A
SCHEMBL11277290 0.80 POLB (0.53) KDM4EALDH1A1PYGLPYGMKMT2A
SCHEMBL9681829 0.80 TP53 (0.54) KDM4EALDH1A1PYGLPYGMMAPT
SCHEMBL9682440 0.80 ALDH1A1 (0.54) KDM4EALDH1A1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153335-A Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst OCCIDENTAL CHEMICAL CORPORATION (US) 1992-10-06 US claimed
EP-0460687-A2 Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-12-11 EP claimed