Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680830 | 0.85 | CYP3A4 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL28008271 | 0.83 | TSHR (0.46) | TSHRTDP1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL19792371 | 0.82 | NPC1 (0.47) | TSHRTDP1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL8991603 | 0.81 | TDP1 (0.47) | TSHRTDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL9681180 | 0.79 | ALDH1A1 (0.46) | TSHRTDP1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL9773152 | 0.79 | NPC1 (0.62) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27296401 | 0.79 | NPC1 (0.62) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9773153 | 0.79 | NPC1 (0.62) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28818249 | 0.79 | TSHR (0.45) | TSHRTDP1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL2420020 | 0.79 | TSHR (0.54) | TSHRTDP1L3MBTL1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492078-A2 | Process for the preparation of butyle esters of 2-phenylecyclopropanecarboxylic acid | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | claimed |
| US-5118834-A | Decyclization of 5-phenylbutyrolactone in hydrochloric acid to give 4-chloro-4-phenylbutanoate; cyclization in sodium hydroxide | HUELS AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| EP-0492078-A2 | Process for the preparation of butyle esters of 2-phenylecyclopropanecarboxylic acid | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| EP-0492078-A2 | Process for the preparation of butyle esters of 2-phenylecyclopropanecarboxylic acid | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-5118834-A | Decyclization of 5-phenylbutyrolactone in hydrochloric acid to give 4-chloro-4-phenylbutanoate; cyclization in sodium hydroxide | HUELS AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |