Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 4/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58163 | 0.92 | CES1 (0.50) | HPGDRAB9ANPC1ALDH1A1TDP1 | |
| SCHEMBL10945414 | 0.92 | HPGD (0.50) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| SCHEMBL10941473 | 0.89 | RAB9A (0.56) | HPGDRAB9ANPC1CES1 | |
| SCHEMBL29242353 | 0.85 | MAPT (0.52) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL9681134 | 0.84 | MAPT (0.68) | HPGDRAB9ANPC1ALDH1A1TDP1 | |
| SCHEMBL14156791 | 0.81 | SMN1; SMN2 (0.53) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| SCHEMBL10943108 | 0.81 | ALDH1A1 (0.56) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| SCHEMBL10384767 | 0.81 | HPGD (0.56) | HPGDRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL17479953 | 0.80 | ALDH1A1 (0.61) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| SCHEMBL10947494 | 0.80 | CES2 (0.44) | HPGDRAB9AALDH1A1MAPTCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0138754-B1 | PHOTOCURABLE COMPOSITIONS | CIBA-GEIGY AG (CH) | 1988-05-25 | — | — | EP | disclosed |
| EP-0138754-A2 | Photocurable compositions | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |