Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12315502 | 0.78 | GAA (0.41) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL2402208 | 0.77 | L3MBTL1 (0.47) | KMT2ANR1H4ALDH1A1MAPTMEN1 | |
| SCHEMBL12532571 | 0.75 | KMT2A (0.63) | KMT2APARP10NR1H4ALDH1A1TP53 | |
| SCHEMBL2402206 | 0.74 | LMNA (0.42) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL402379 | 0.74 | KMT2A (0.61) | KMT2APARP10NR1H4ALDH1A1TP53 | |
| SCHEMBL2398977 | 0.73 | THRA (0.39) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL25797231 | 0.73 | KMT2A (0.56) | KMT2APARP10NR1H4ALDH1A1TP53 | |
| SCHEMBL9681265 | 0.72 | BCHE (0.46) | KMT2APARP10ALDH1A1MAPTLMNA | |
| SCHEMBL22548942 | 0.71 | KMT2A (0.58) | KMT2APARP10NR1H4ALDH1A1TP53 | |
| SCHEMBL22548977 | 0.71 | KMT2A (0.58) | KMT2APARP10NR1H4ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |