Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681707 | 0.81 | HDAC1 (0.49) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL10458476 | 0.80 | CES2 (0.53) | RAB9ACES2CES1ALDH1A1LMNA | |
| SCHEMBL57578 | 0.80 | CES2 (0.53) | RAB9ACES2CES1ALDH1A1LMNA | |
| SCHEMBL9679513 | 0.79 | HDAC3 (0.48) | MEN1CYP2D6HTTKMT2ANPC1 | |
| SCHEMBL9681281 | 0.77 | CA1 (0.47) | MEN1KMT2ANPC1RAB9ADRD2 | |
| SCHEMBL9681297 | 0.76 | CES2 (0.48) | BCHERAB9ACES2CES1ALDH1A1 | |
| SCHEMBL757101 | 0.73 | CES2 (0.61) | MEN1KMT2ARAB9ACES2CES1 | |
| SCHEMBL9681272 | 0.72 | KMT2A (0.47) | MEN1HTTKMT2ANPC1RAB9A | |
| SCHEMBL10891605 | 0.72 | THRB (0.56) | BCHEACHEMAPT | |
| SCHEMBL11258091 | 0.72 | KDM4E (0.49) | MEN1CYP2D6KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |