Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9133425 | 0.82 | MTNR1A (0.42) | CYP4F2CYP4A11CASRDRD2DRD3 | |
| SCHEMBL9130726 | 0.82 | MTNR1A (0.42) | CYP4F2CYP4A11CASRDRD2DRD3 | |
| SCHEMBL9136926 | 0.82 | MTNR1A (0.42) | CYP4F2CYP4A11CASRDRD2DRD3 | |
| SCHEMBL9133100 | 0.77 | DRD2 (0.43) | CYP4F2CYP4A11HRH3CASRDRD2 | |
| SCHEMBL9132654 | 0.77 | MTNR1A (0.40) | CYP4Z1DRD2DRD3 | |
| SCHEMBL9132112 | 0.77 | CASR (0.41) | CYP4F2CYP4A11HRH3CASRDRD2 | |
| SCHEMBL9675028 | 0.76 | CYP4F2 (0.41) | CYP4F2CYP4A11HRH3CASRCYP4Z1 | |
| SCHEMBL9672071 | 0.74 | CYP4F2 (0.43) | CYP4F2CYP4A11HRH3CASRCYP4Z1 | |
| SCHEMBL24528893 | 0.74 | HRH3 (0.44) | CYP4F2CYP4A11HRH3CASRRECQL | |
| SCHEMBL8768133 | 0.74 | POLB (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500443-A1 | Phenylethanolamino- and phenylethanolaminomethyltetralines, process for their preparation, intermediates of this process and pharmaceutical compositions containing them | SANOFI (FR) | 1992-08-26 | — | — | EP | disclosed |