SCHEMBL9681504

SCHEMBL9681504

CC(C)(C)c1ccc(P(c2ccc(C(C)(C)C)cc2)c2ccc3ccccc3c2-c2cccc3ccccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
HSD17B2 P37059 1/20 0.38
NR1I2 O75469 1/20 0.37
LMNA P02545 1/20 0.37
ADRA2A P08913 1/20 0.37
CYP2D6 P10635 1/20 0.37
ACHE P22303 1/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2A P28223 1/20 0.37
SLC6A4 P31645 1/20 0.37
KCNH2 Q12809 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
GPR84 Q9NQS5 1/20 0.36
NLRP3 Q96P20 1/20 0.36
DHFR P00374 1/20 0.35
KDR P35968 1/20 0.34
GSK3B P49841 1/20 0.34
ADK P55263 1/20 0.34
MEN1 O00255 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1044125 0.90 HSD17B2 (0.42) HSP90AA1HSP90AB1HSD17B2NR1I2LMNA
Bromide SCHEMBL7937216 0.87 HSD17B2 (0.40) HSP90AA1HSP90AB1HSD17B2NR1I2LMNA
Hydrochloric Acid SCHEMBL7937212 0.87 HSD17B2 (0.40) HSP90AA1HSP90AB1HSD17B2NR1I2LMNA
Iodide SCHEMBL7946567 0.87 HSD17B2 (0.40) HSP90AA1HSP90AB1HSD17B2NR1I2LMNA
Fluoride Ion SCHEMBL7946277 0.87 HSD17B2 (0.40) HSP90AA1HSP90AB1HSD17B2NR1I2LMNA
SCHEMBL7796059 0.86 KCNQ3 (0.34) LMNASLC6A4DHFRGSK3BADK
SCHEMBL2949327 0.84 DHFR (0.40) GPR84DHFRGSK3BADKMEN1
SCHEMBL275907 0.84 DNMT1 (0.40) LMNAGPR84DHFRGSK3BADK
SCHEMBL29368065 0.84 DNMT1 (0.40) LMNAGPR84DHFRGSK3BADK
SCHEMBL30616100 0.84 DNMT1 (0.40) LMNAGPR84DHFRGSK3BADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5144050-A Hydrogenation Catalysts MONSANTO COMPANY (US) 1992-09-01 US disclosed