SCHEMBL9681758

SCHEMBL9681758

COc1ccc(C(S)C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.52
AKR1C3 P42330 6/20 0.50
AKR1C2 P52895 6/20 0.50
PTGS2 P35354 3/20 0.50
PTGS1 P23219 3/20 0.50
CYP1A2 P05177 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CDC42 P60953 1/20 0.50
RAC1 P63000 1/20 0.50
TSHR P16473 1/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
ACP3 P15309 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
NPSR1 Q6W5P4 2/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11780191 0.84 AKR1C3 (0.69) AKR1C3AKR1C2PTGS2PTGS1CYP1A2
SCHEMBL997295 0.82 SRC (0.42) AKR1C3PTGS2PTGS1SLC22A6ALDH1A1
SCHEMBL11210447 0.82 CES2 (0.45) LDHACA1CA2TSHRACP3
SCHEMBL5901682 0.82 CA1 (0.52) CA1CA2ACP3L3MBTL1CES2
SCHEMBL7377562 0.79 CA1 (0.50) LDHAAKR1C3AKR1C2PTGS2PTGS1
SCHEMBL1451206 0.79 RAB9A (0.57) LDHAAKR1C3AKR1C2PTGS2PTGS1
SCHEMBL7044804 0.79 LDHA (0.55) LDHAAKR1C3AKR1C2PTGS2PTGS1
SCHEMBL11872454 0.78 CA1 (0.51) CA1CA2ALDH1A1CES2CES1
SCHEMBL350067 0.78 PTGS2 (0.71) LDHAAKR1C3AKR1C2PTGS2PTGS1
SCHEMBL4634271 0.78 TSHR (0.56) LDHAAKR1C3AKR1C2PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102838578-B Salt and cured composition for color SUMITOMO CHEMICAL CO.,LTD. (JP) 2016-03-16 CN disclosed
CN-105408427-A Compound and colored curable resin composition DONGWOO FINE CHEM CO LTD 2016-03-16 CN disclosed
CN-105263968-A Colored curable resin composition DONGWOO FINE CHEM CO LTD 2016-01-20 CN disclosed
CN-105198805-A Compound and coloring curable resin composition SUMITOMO CHEMICAL CO 2015-12-30 CN disclosed
US-5087631-A Vasodilators for treating cardiovascular disorders GLAXO INC. (US) 1992-02-11 US disclosed
US-4461911-A FROM THIOGLYCOLIC ACID AND AN ARYLDIAZONIUM SALT, COPPER SALT, ACID MEDIUM BAYER AKTIENGESELLSCHAFT (DE) 1984-07-24 US disclosed