Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378101 | 0.79 | KMT2A (0.49) | RAB9AMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL9681761 | 0.75 | ALDH1A1 (0.38) | L3MBTL1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6787347 | 0.74 | ALOX15 (0.49) | TDP1L3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL6844006 | 0.73 | CYP1A2 (0.56) | L3MBTL1RAB9AALDH1A1CYP1A2NPC1 | |
| SCHEMBL8933321 | 0.73 | ALDH1A1 (0.47) | L3MBTL1RAB9AMEN1KMT2AHTT | |
| SCHEMBL983848 | 0.73 | CYP1A2 (0.56) | L3MBTL1RAB9AALDH1A1CYP1A2NPC1 | |
| SCHEMBL8472341 | 0.73 | NPSR1 (0.47) | TDP1L3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL7473317 | 0.72 | PARP10 (0.52) | RAB9AMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL3089210 | 0.70 | ALDH1A1 (0.62) | RAB9AMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9276547 | 0.69 | NPSR1 (0.54) | TDP1L3MBTL1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087631-A | Vasodilators for treating cardiovascular disorders | GLAXO INC. (US) | 1992-02-11 | — | — | US | disclosed |