Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680641 | 0.87 | TOP1 (0.64) | KMT2ATOP1LMNAPTGESALDH1A1 | |
| SCHEMBL11015465 | 0.78 | KMT2A (0.51) | KMT2ATOP1LMNANPC1NR1I2 | |
| SCHEMBL2176042 | 0.75 | KDM4E (0.50) | KMT2ALMNATP53ALDH1A1HTT | |
| SCHEMBL9681102 | 0.72 | MAPT (0.60) | KMT2APTGESALDH1A1HTTMAPT | |
| SCHEMBL19509566 | 0.72 | KMT2A (0.77) | KMT2ATOP1LMNANPC1NR1I2 | |
| SCHEMBL11908091 | 0.72 | ELANE (0.39) | KMT2ATOP1LMNANPC1TP53 | |
| SCHEMBL27957751 | 0.72 | POLM (0.46) | KMT2ATOP1LMNAALDH1A1TYMS | |
| SCHEMBL29445347 | 0.72 | TYMS (0.57) | KMT2ATOP1LMNANPC1TP53 | |
| SCHEMBL22091025 | 0.72 | KMT2A (0.58) | KMT2ALMNANPC1NR1I2TP53 | |
| SCHEMBL966421 | 0.72 | TYMS (0.57) | KMT2ATOP1LMNANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | claimed |