Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281450 | 0.83 | RAB9A (0.41) | MAPTRAB9ANPC1ELANELMNA | |
| SCHEMBL9268706 | 0.81 | RAB9A (0.48) | MAPTRAB9ANPC1ELANELMNA | |
| SCHEMBL9431965 | 0.81 | RAB9A (0.40) | MAPTRAB9ANPC1ELANELMNA | |
| SCHEMBL9681377 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL9432441 | 0.79 | RAB9A (0.43) | MAPTRAB9ANPC1ELANELMNA | |
| SCHEMBL9456135 | 0.78 | — | — | |
| SCHEMBL9682726 | 0.76 | RAB9A (0.39) | MAPTRAB9ANPC1ELANELMNA | |
| SCHEMBL9681865 | 0.72 | C1R (0.39) | MAPTRAB9ANPC1ELANELMNA | |
| SCHEMBL9846349 | 0.72 | MAPT (0.50) | MAPTRAB9ANPC1ELANELMNA | |
| SCHEMBL9846171 | 0.71 | MAPT (0.40) | MAPTRAB9ANPC1ELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |