SCHEMBL9770940

SCHEMBL9770940

Cc1ccc2c(c1Cl)C(=O)N(C1(C(N)=O)CCCCC1)C2=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.32
GAA P10253 1/20 0.31
CYP2C19 P33261 1/20 0.31
PDE7A Q13946 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5933663 0.79 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTTSHRCYP2C19
SCHEMBL11731118 0.79 ESR1 (0.36) ALDH1A1KDM4EMAPTTSHRGAA
SCHEMBL9682755 0.77 CA9 (0.42) ALDH1A1KDM4ETSHR
SCHEMBL9682128 0.77 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTCYP2C19
SCHEMBL9681285 0.77 ALDH1A1 (0.44) ALDH1A1KDM4EMAPT
SCHEMBL10333899 0.77 CA12 (0.37) ALDH1A1KDM4ECYP2C19
SCHEMBL11728138 0.76 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTTSHR
SCHEMBL9845601 0.76 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTTSHRGAA
SCHEMBL9770937 0.75 PDE7A (0.31) GAAPDE7A
SCHEMBL11728360 0.74 ALDH1A1 (0.58) ALDH1A1KDM4EMAPTTSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5073190-A Substituted phthalimido cyclohexanecarboxamides and compositions thereof for enhancing growth of hybrid tea rose plants AMERICAN CYANAMID COMPANY (US) 1991-12-17 US claimed
US-5019154-A Plant growth regulators AMERICAN CYANAMID COMPANY (US) 1991-05-28 US claimed
EP-0427907-A2 Substituted phthalimido cyclohexanecarboxamides and the use thereof for enhancing growth of hybrid tea rose plants AMERICAN CYANAMID COMPANY (US) 1991-05-22 EP claimed
JP-3181460-A None JP disclosed
US-5073190-A Substituted phthalimido cyclohexanecarboxamides and compositions thereof for enhancing growth of hybrid tea rose plants AMERICAN CYANAMID COMPANY (US) 1991-12-17 US disclosed
US-5073190-A Substituted phthalimido cyclohexanecarboxamides and compositions thereof for enhancing growth of hybrid tea rose plants AMERICAN CYANAMID COMPANY (US) 1991-12-17 US disclosed
JP-H03181460-A SUBSTITUTED PHTHALIMIDO CYCLOHEXANECARBOXAMIDES AND THE USE THEREOF FOR ENHACING GROWTH OF HYBRID TEA ROSE PLANTS AMERICAN CYANAMID CO 1991-08-07 JP disclosed
US-5019154-A Plant growth regulators AMERICAN CYANAMID COMPANY (US) 1991-05-28 US disclosed
US-5019154-A Plant growth regulators AMERICAN CYANAMID COMPANY (US) 1991-05-28 US disclosed
EP-0427907-A2 Substituted phthalimido cyclohexanecarboxamides and the use thereof for enhancing growth of hybrid tea rose plants AMERICAN CYANAMID COMPANY (US) 1991-05-22 EP disclosed
EP-0427907-A2 Substituted phthalimido cyclohexanecarboxamides and the use thereof for enhancing growth of hybrid tea rose plants AMERICAN CYANAMID COMPANY (US) 1991-05-22 EP disclosed