Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720374 | 0.87 | MEN1 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL2521152 | 0.78 | LTA4H (0.58) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL9198034 | 0.77 | F2 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL9540409 | 0.77 | LMNA (0.43) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8941674 | 0.74 | F2 (0.46) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL954527 | 0.74 | LOXL2 (0.48) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL15871857 | 0.74 | LOXL2 (0.55) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL10544524 | 0.73 | F2 (0.39) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL3367184 | 0.73 | F2 (0.41) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6316219 | 0.71 | F2 (0.40) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361694-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-04 | — | — | EP | claimed |
| EP-0361695-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-04 | — | — | EP | claimed |
| EP-0295839-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-21 | — | — | EP | claimed |
| EP-0223521-A2 | Insecticidal and acaricidal phenoxypyridinyl esters and intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-27 | — | — | EP | claimed |
| US-5091416-A | INSECTICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |
| US-5026727-A | 1,1-Difluoro-2-alkyl-2-(4-trifluoromethoxy-phenyl)-3-(substituted benzyloxy) propane | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-25 | — | — | US | disclosed |
| US-5010200-A | Insecticide intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-23 | — | — | US | disclosed |
| US-4962109-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-09 | — | — | US | disclosed |
| EP-0361694-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-04 | — | — | EP | disclosed |
| EP-0361695-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-04 | — | — | EP | disclosed |
| EP-0295839-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4694013-A | Insecticidal and acaricidal phenoxypyrdinyl esters and intermediates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0223521-A2 | Insecticidal and acaricidal phenoxypyridinyl esters and intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-27 | — | — | EP | disclosed |