Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650078 | 1.00 | MGAM (0.44) | MGAMGAASIMGAM2ALOX15 | |
| SCHEMBL4682244 | 1.00 | MGAM (0.44) | MGAMGAASIMGAM2ALOX15 | |
| SCHEMBL804645 | 0.96 | MGAM (0.41) | MGAMGAASIMGAM2ALOX15 | |
| Acetoacetic Acid SCHEMBL2189217 | 0.83 | MGAM (0.33) | MGAMGAASIMGAM2ALOX15 | |
| SCHEMBL17481290 | 0.83 | MMP1 (0.38) | ALOX15TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL13978415 | 0.83 | MGAM (0.56) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL19864353 | 0.83 | MGAM (0.56) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL12922365 | 0.82 | MGAM (0.54) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL944289 | 0.81 | MGAM (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL29124665 | 0.80 | CYP1A2 (0.40) | ALOX15TDP1KDM6BKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634430-B1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2024-08-07 | — | — | EP | disclosed |
| EP-4267121-A1 | KETONE BODY ESTERS OF S-BETA-HYDROXYBUTYRATE AND/OR S-1,3-BUTANEDIOL FOR MODIFYING METABOLIC FUNCTION | Axcess Global Sciences, LLC (US) | 2023-11-01 | — | — | EP | disclosed |
| US-11786499-B2 | Ketone body esters of S-beta-hydroxybutyrate and/or S-1,3-butanediol for modifying metabolic function | AXCESS GLOBAL SCIENCES, LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230293458-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230293458-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2023-09-21 | — | — | US | disclosed |
| WO-2022140130-A1 | KETONE BODY ESTERS OF S-BETA-HYDROXYBUTYRATE AND/OR S-1,3-BUTANEDIOL FOR MODIFYING METABOLIC FUNCTION | AXCESS GLOBAL SCIENCES, LLC (US) | 2022-06-30 | — | — | WO | disclosed |
| US-20220133673-A1 | KETONE BODY ESTERS OF S-BETA-HYDROXYBUTYRATE AND/OR S-1,3-BUTANEDIOL FOR MODIFYING METABOLIC FUNCTION | AXCESS GLOBAL SCIENCES, LLC | 2022-05-05 | — | — | US | disclosed |
| US-11202769-B2 | Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function | AXCESS GLOBAL SCIENCES, LLC (US) | 2021-12-21 | — | — | US | disclosed |
| US-20210169831-A1 | KETONE BODY ESTERS OF S-BETA-HYDROXYBUTYRATE AND/OR S-1,3-BUTANEDIOL FOR MODIFYING METABOLIC FUNCTION | AXCESS GLOBAL SCIENCES, LLC | 2021-06-10 | — | — | US | disclosed |
| EP-3634430-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | Flagship Pioneering Innovations V, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| US-20200101030-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | KINTAI THERAPEUTICS, INC. | 2020-04-02 | — | — | US | disclosed |
| CN-110869024-A | Multi-biological agents and methods of use thereof | 旗舰创业创新五公司 | 2020-03-06 | — | — | CN | disclosed |
| WO-2018226732-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2018-12-13 | — | — | WO | disclosed |
| US-5126373-A | Ester or diester of 1,3-butanediol or 1,3-pentanediol; side effect reduction | BRUNENGRABER HENRI (US) | 1992-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220133673-A1 | KETONE BODY ESTERS OF S-BETA-HYDROXYBUTYRATE AND/OR S-1,3-BUTANEDIOL FOR MODIFYING METABOLIC FUNCTION | HADHB, BCKDK, CPT1B | MGAM 1292/4885GAA 3807/4885SI 453/4885 |
| US-11786499-B2 | Ketone body esters of S-beta-hydroxybutyrate and/or S-1,3-butanediol for modifying metabolic function | HADHB, BCKDK, CPT1B | MGAM 1292/4885GAA 3807/4885SI 453/4885 |
| US-11202769-B2 | Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function | HADHB, BCKDK, CPT1B | MGAM 1292/4885GAA 3807/4885SI 453/4885 |
| US-20210169831-A1 | KETONE BODY ESTERS OF S-BETA-HYDROXYBUTYRATE AND/OR S-1,3-BUTANEDIOL FOR MODIFYING METABOLIC FUNCTION | HADHB, BCKDK, CPT1B | MGAM 1292/4885GAA 3807/4885SI 453/4885 |
| US-20200101030-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | SI, FABP2, CEL | MGAM 8/4885GAA 177/4885SI 1/4885 |
| US-20230293458-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | SI, FABP2, CEL | MGAM 8/4885GAA 177/4885SI 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.