SCHEMBL9682405

SCHEMBL9682405

C/C=C/Cc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.71
AGTR2 P50052 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153 1.00 AGTR1 (0.71) AGTR1AGTR2
SCHEMBL10586961 0.90 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL409 0.89 AGTR2 (0.57) AGTR1AGTR2
SCHEMBL9682924 0.87 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL137 0.87 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL8792409 0.85 AGTR1 (0.53) AGTR1AGTR2
SCHEMBL9636909 0.83 PPARG (0.63) AGTR1AGTR2
SCHEMBL29486822 0.83 AGTR1 (1.00) AGTR1AGTR2
SCHEMBL89 0.83 AGTR1 (1.00) AGTR1AGTR2
SCHEMBL9468476 0.82 AGTR1 (0.98) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128355-A Hypotensive E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-07 US disclosed