Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137 | 1.00 | AGTR1 (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL10587698 | 0.90 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL418 | 0.90 | SLC6A4 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9683629 | 0.90 | SLC6A4 (0.46) | AGTR1AGTR2 | |
| SCHEMBL153 | 0.87 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL9682405 | 0.87 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL33 | 0.84 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL9636909 | 0.81 | PPARG (0.63) | AGTR1AGTR2PPARG | |
| SCHEMBL138 | 0.80 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL136 | 0.80 | AGTR1 (0.52) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |