Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 6/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681975 | 0.87 | GAA (0.41) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9683852 | 0.86 | TDP1 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9683010 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL10679118 | 0.78 | GABRA2 (0.43) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9723106 | 0.78 | GABRA2 (0.40) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL10678078 | 0.75 | GABRA2 (0.40) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9681941 | 0.74 | TDP1 (0.47) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9684212 | 0.74 | GAA (0.33) | ALDH1A1 | |
| SCHEMBL10678734 | 0.72 | GABRA2 (0.38) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9339490 | 0.71 | GABRA2 (0.38) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3048667-A | — | — | None | — | — | JP | disclosed |
| US-5079251-A | Insecticides, pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| JP-H0348667-A | PYRAZINONE DERIVATIVE, PREPARATION THEREOF, INSECTICIDAL AND ACARICIDAL COMPOSITION AND METHOD OF KILLING INSECT AND ACARINE | IMPERIAL CHEM IND PLC <ICI> | 1991-03-01 | — | — | JP | disclosed |
| EP-0408196-A2 | Pyrazinone derivatives as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-16 | — | — | EP | disclosed |