Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682464 | 0.83 | GABRA2 (0.43) | ALDH1A1MAPTKMT2AHTT | |
| SCHEMBL10701517 | 0.83 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTNPC1RAB9A | |
| SCHEMBL10700184 | 0.82 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTNPC1RAB9A | |
| SCHEMBL9765814 | 0.81 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTNPC1RAB9A | |
| SCHEMBL10700256 | 0.78 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTNPC1RAB9A | |
| SCHEMBL5858296 | 0.78 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTNPC1RAB9A | |
| SCHEMBL10457648 | 0.76 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTNPC1RAB9A | |
| SCHEMBL9681975 | 0.75 | GAA (0.41) | ALDH1A1TDP1GAACYP3A4SMN1; SMN2 | |
| SCHEMBL9683852 | 0.74 | TDP1 (0.46) | ALDH1A1POLBMAPTNPC1RAB9A | |
| SCHEMBL10701906 | 0.73 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079251-A | Insecticides, pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| EP-0408196-A2 | Pyrazinone derivatives as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-16 | — | — | EP | disclosed |