Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683781 | 0.82 | ALDH1A1 (0.47) | TDP1MAPTSMN1; SMN2 | |
| SCHEMBL9681939 | 0.79 | EPHX2 (0.47) | RAB9ANPC1CYP2D6CHRM4MAPT | |
| SCHEMBL9682501 | 0.74 | CYP2D6 (0.42) | CYP2D6SMN1; SMN2MC4RCCR5 | |
| SCHEMBL9682612 | 0.73 | CYP2D6 (0.52) | CYP2D6MAPTSMN1; SMN2MC4RCCR5 | |
| SCHEMBL28155957 | 0.71 | TDP1 (0.59) | NFE2L2TDP1RAB9ANPC1GAA | |
| SCHEMBL9684280 | 0.71 | CYP2D6 (0.49) | CYP2D6MAPTSMN1; SMN2MC4RCCR5 | |
| SCHEMBL2920210 | 0.70 | CYP2D6 (0.61) | CYP2D6MC4RCCR5 | |
| SCHEMBL2562093 | 0.70 | NFE2L2 (0.83) | NFE2L2TDP1RAB9ANPC1GAA | |
| SCHEMBL2921816 | 0.70 | CYP2D6 (0.61) | CYP2D6MC4RCCR5 | |
| SCHEMBL9681972 | 0.70 | CYP2D6 (0.47) | CYP2D6MAPTSMN1; SMN2MC4RCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | claimed |
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |