Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682553 | 0.79 | NFE2L2 (0.49) | CHRM4SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL9683781 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL9682087 | 0.71 | OPRL1 (0.44) | CHRM4ALDH1A1RAB9ACYP2D6MAPT | |
| SCHEMBL9682542 | 0.70 | CYP2D6 (0.47) | CHRM4SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL11338762 | 0.70 | GPR174 (0.56) | EPHX2PPARASMN1; SMN2GPR174MEN1 | |
| SCHEMBL9682501 | 0.69 | CYP2D6 (0.42) | SMN1; SMN2LMNAALDH1A1CYP2D6 | |
| SCHEMBL27710655 | 0.69 | CA12 (0.65) | EPHX2SMN1; SMN2LMNAL3MBTL1MEN1 | |
| SCHEMBL9682612 | 0.69 | CYP2D6 (0.52) | SMN1; SMN2LMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL9683068 | 0.68 | KMT2A (0.46) | SMN1; SMN2LMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL27710659 | 0.68 | RAB9A (0.71) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | claimed |
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |