Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122107 | 0.87 | SCN9A (0.47) | CYP2D6CHRM2CHRM1ALDH1A1SCN7A | |
| SCHEMBL9682501 | 0.86 | CYP2D6 (0.42) | CYP2D6MC4RCCR5CHRM2CHRM1 | |
| SCHEMBL7093869 | 0.80 | KMT2A (0.52) | CYP2D6ALDH1A1 | |
| SCHEMBL7096693 | 0.80 | KMT2A (0.52) | CYP2D6ALDH1A1 | |
| SCHEMBL9684294 | 0.78 | CYP2D6 (0.49) | CYP2D6MC4RCCR5CHRM2CHRM1 | |
| SCHEMBL14168007 | 0.74 | HTR2B (0.46) | — | |
| SCHEMBL9683895 | 0.73 | CYP2D6 (0.55) | CYP2D6MC4RCCR5ALDH1A1LMNA | |
| SCHEMBL9683868 | 0.73 | SCN4A (0.46) | CYP2D6MC4RALDH1A1FFAR1SCN7A | |
| SCHEMBL8573441 | 0.73 | LMNA (0.48) | CYP2D6MC4RCCR5CHRM2CHRM1 | |
| SCHEMBL9683068 | 0.71 | KMT2A (0.46) | CYP2D6ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |