Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682149 | 0.84 | CA2 (1.00) | CA2 | |
| SCHEMBL8950255 | 0.73 | CA2 (1.00) | CA2 | |
| SCHEMBL9683126 | 0.70 | CA2 (0.70) | CA2 | |
| SCHEMBL10513850 | 0.65 | CA2 (0.48) | CA2 | |
| SCHEMBL9429746 | 0.62 | CA2 (0.62) | CA2 | |
| SCHEMBL3788186 | 0.62 | CA2 (0.43) | CA2 | |
| SCHEMBL10513455 | 0.62 | CA2 (1.00) | CA2 | |
| SCHEMBL9682131 | 0.62 | CA2 (0.61) | CA2 | |
| SCHEMBL9683786 | 0.62 | CA2 (0.61) | CA2 | |
| Hydrochloric Acid SCHEMBL9429811 | 0.61 | CA2 (0.61) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479480-A2 | Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | claimed |
| US-5093332-A | SUBSTITUTED THIENO(2,3-B)(1,4)THIAZINE-6-SULFONAMIDES AS ANTIGLAUCOMA AGENTS | MERCK & CO., INC. (US) | 1992-03-03 | — | — | US | claimed |
| EP-0479480-A2 | Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| US-5093332-A | SUBSTITUTED THIENO(2,3-B)(1,4)THIAZINE-6-SULFONAMIDES AS ANTIGLAUCOMA AGENTS | MERCK & CO., INC. (US) | 1992-03-03 | — | — | US | disclosed |