Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 7/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068710 | 0.95 | MME (0.55) | PAMACEMMECPA1ACE2 | |
| SCHEMBL9068920 | 0.87 | LTA4H (0.52) | PAMACEMMEECE1 | |
| SCHEMBL27521411 | 0.81 | ACE (0.63) | ACENAALAD2MMEL3MBTL1CPA1 | |
| SCHEMBL3818234 | 0.81 | ACE (0.63) | ACENAALAD2MMEL3MBTL1CPA1 | |
| SCHEMBL6293500 | 0.80 | ALDH1A1 (0.64) | ACENAALAD2MMEL3MBTL1CPA1 | |
| SCHEMBL995229 | 0.80 | ALDH1A1 (0.64) | ACENAALAD2MMEL3MBTL1CPA1 | |
| SCHEMBL995228 | 0.80 | ALDH1A1 (0.64) | ACENAALAD2MMEL3MBTL1CPA1 | |
| SCHEMBL4182347 | 0.80 | ACE (0.61) | ACENAALAD2MMEL3MBTL1CPA1 | |
| SCHEMBL10076052 | 0.80 | ACE (0.61) | ACENAALAD2MMEL3MBTL1CPA1 | |
| SCHEMBL3704677 | 0.80 | ACE (0.61) | ACENAALAD2MMEL3MBTL1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470494-A1 | Active site labelling of plasminogen | HENRY FORD HEALTH SYSTEM, d/b/a HENRY FORD HOSPITAL (US) | 1992-02-12 | — | — | EP | claimed |
| EP-0470494-A1 | Active site labelling of plasminogen | HENRY FORD HEALTH SYSTEM, d/b/a HENRY FORD HOSPITAL (US) | 1992-02-12 | — | — | EP | disclosed |