Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.64 |
| ▸ | MME | P08473 | 3/20 | 0.59 |
| ▸ | ACE | P12821 | 7/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CTSG | P08311 | 1/20 | 0.57 |
| ▸ | CMA1 | P23946 | 1/20 | 0.57 |
| ▸ | FPR2 | P25090 | 1/20 | 0.57 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CPA1 | P15085 | 2/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293500 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL995228 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL3510328 | 0.87 | ACE (0.60) | MMEACENAALAD2CPA1ACE2 | |
| SCHEMBL3510333 | 0.87 | ACE (0.60) | MMEACENAALAD2CPA1ACE2 | |
| SCHEMBL16892795 | 0.87 | ACE (0.60) | MMEACENAALAD2CPA1ACE2 | |
| SCHEMBL23489727 | 0.87 | ALDH1A1 (0.63) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL514883 | 0.87 | ACE (0.62) | MMEACENPSR1CTSGCMA1 | |
| SCHEMBL28952171 | 0.87 | ACE (0.62) | MMEACENPSR1CTSGCMA1 | |
| SCHEMBL29981912 | 0.86 | FOLH1 (0.52) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL11503757 | 0.86 | NOS2 (0.54) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240183860-A1 | Chimeric ABC Transporters and Screening Methods | GENENTECH, INC. (US) | 2024-06-06 | — | — | US | claimed |
| EP-4330689-A2 | CHIMERIC ABC TRANSPORTERS AND SCREENING METHODS | Genentech, Inc. (US) | 2024-03-06 | — | — | EP | claimed |
| CN-117203529-A | Chimeric ABC transporter and screening method | 基因泰克公司 | 2023-12-08 | — | — | CN | claimed |
| WO-2022232125-A2 | CHIMERIC ABC TRANSPORTERS AND SCREENING METHODS | GENENTECH, INC. (US) | 2022-11-03 | — | — | WO | claimed |
| US-20100130416-A1 | MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS | ARCHER PHARMACEUTICALS, INC. (US) | 2010-05-27 | — | — | US | claimed |
| WO-2009143489-A2 | MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS | ARCHER PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | claimed |
| US-12565517-B2 | Cyclic peptide having CTLA-4 inhibitory activity and use thereof | GENEFRONTIER CORPORATION (JP) | 2026-03-03 | — | — | US | disclosed |
| EP-3947671-B1 | METHODS OF SELECTING AND DETECTING BINDING PEPTIDES | LILLY CO ELI (US) | 2025-09-17 | — | — | EP | disclosed |
| EP-4043076-B1 | CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF | GENEFRONTIER CORP (JP) | 2024-06-26 | — | — | EP | disclosed |
| US-20240183860-A1 | Chimeric ABC Transporters and Screening Methods | GENENTECH, INC. (US) | 2024-06-06 | — | — | US | disclosed |
| US-11946042-B2 | Modification of D- and T-arms of tRNA enhancing D-amino acid and β-amino acid uptake | THE UNIVERSITY OF TOKYO (JP) | 2024-04-02 | — | — | US | disclosed |
| US-20240092836-A1 | CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF | GENEFRONTIER CORPORATION (JP) | 2024-03-21 | — | — | US | disclosed |
| EP-4330689-A2 | CHIMERIC ABC TRANSPORTERS AND SCREENING METHODS | Genentech, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| US-4414404-A | FROM N-ACYL-ACETAMINOCINNAMIC ACID AZLACTONE | ETHYL CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0028251-B1 | PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER | ETHYL CORPORATION (US) | 1983-03-16 | — | — | EP | disclosed |
| EP-0028251-A1 | PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER. | ETHYL CORP (US) | 1981-05-13 | — | — | EP | disclosed |
| US-4262092-A | Process for producing N-acyl-D-phenylalanine ester | ETHYL CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |
| EP-0028251-A4 | PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER. | ETHYL CORP (US) | 1981-03-27 | — | — | EP | disclosed |
| WO-1980002421-A1 | PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER | ETHYL CORP (US) | 1980-11-13 | — | — | WO | disclosed |
| US-4055663-A | Halogenated acylamino acids as fungicides | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092836-A1 | CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF | CXCL10, CXCR3, CXCR6 | ALDH1A1 4745/4885HTT 3771/4885NCOA1 3589/4885 |
| US-12565517-B2 | Cyclic peptide having CTLA-4 inhibitory activity and use thereof | CXCL10, MLX, MICA | ALDH1A1 4840/4885HTT 3448/4885NCOA1 3048/4885 |
| US-20100130416-A1 | MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS | VEGFA, APP, IAPP | ALDH1A1 2501/4885HTT 109/4885NCOA1 4310/4885 |
| US-20240183860-A1 | Chimeric ABC Transporters and Screening Methods | ABCB4, ABCE1, ABCD3 | ALDH1A1 3456/4885HTT 1904/4885NCOA1 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.