Sugi Predict

Sugi Predict / Compounds / SCHEMBL995228

SCHEMBL995228

SCHEMBL995228

O=C(CCl)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.64
▸ HTT P42858 1/20 0.64
▸ NCOA1 Q15788 1/20 0.64
▸ SMN1; SMN2 Q16637 1/20 0.64
▸ NCOA3 Q9Y6Q9 1/20 0.64
▸ MME P08473 3/20 0.59
▸ ACE P12821 7/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.58
▸ CTSG P08311 1/20 0.57
▸ CMA1 P23946 1/20 0.57
▸ FPR2 P25090 1/20 0.57
▸ NAALAD2 Q9Y3Q0 1/20 0.56
▸ ECE1 P42892 1/20 0.56
▸ LMNA P02545 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ CPA1 P15085 2/20 0.55
▸ ACE2 Q9BYF1 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293500 1.00 ALDH1A1 (0.64) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL995229 1.00 ALDH1A1 (0.64) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL3510328 0.87 ACE (0.60) MMEACENAALAD2CPA1ACE2
SCHEMBL3510333 0.87 ACE (0.60) MMEACENAALAD2CPA1ACE2
SCHEMBL16892795 0.87 ACE (0.60) MMEACENAALAD2CPA1ACE2
SCHEMBL23489727 0.87 ALDH1A1 (0.63) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL514883 0.87 ACE (0.62) MMEACENPSR1CTSGCMA1
SCHEMBL28952171 0.87 ACE (0.62) MMEACENPSR1CTSGCMA1
SCHEMBL29981912 0.86 FOLH1 (0.52) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL11503757 0.86 NOS2 (0.54) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240183860-A1 Chimeric ABC Transporters and Screening Methods GENENTECH, INC. (US) 2024-06-06 — — US claimed
EP-4330689-A2 CHIMERIC ABC TRANSPORTERS AND SCREENING METHODS Genentech, Inc. (US) 2024-03-06 — — EP claimed
CN-117203529-A Chimeric ABC transporter and screening method 基因泰克公司 2023-12-08 — — CN claimed
WO-2022232125-A2 CHIMERIC ABC TRANSPORTERS AND SCREENING METHODS GENENTECH, INC. (US) 2022-11-03 — — WO claimed
WO-2022104001-A1 EXPANDED PROTEIN LIBRARIES AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2022-05-19 — — WO claimed
US-20100130416-A1 MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS ARCHER PHARMACEUTICALS, INC. (US) 2010-05-27 — — US claimed
US-7629154-B2 Process for preparing highly optically pure L-amino acids, such as L-homophenylalanine (L-HPA) and the derivatives thereof, from N-protected amino acid by using the novel NAAAR combined with L-N-carbamoylase NATIONAL CHUNGHSING UNIVERSITY (TW) 2009-12-08 — — US claimed
WO-2009143489-A2 MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS ARCHER PHARMACEUTICALS, INC. (US) 2009-11-26 — — WO claimed
WO-2006092640-A1 ANTIPROLIFERATIVE PEPTIDES CONTAINING THE MOTIF PHE-TRP-LEU, PHARMACEUTICAL COMPOSITIONS AND MEDICAL USES THEREOF OROSZ ANTAL (HU) 2006-09-08 — — WO claimed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 — — EP disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 — — EP disclosed
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 — — US disclosed
EP-4722228-A1 NEW COMPOUND TARGETING MUSK AND USE THEREOF The University of Tokyo (JP) 2026-04-08 — — EP disclosed
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof GENEFRONTIER CORPORATION (JP) 2026-03-03 — — US disclosed
US-4262092-A Process for producing N-acyl-D-phenylalanine ester ETHYL CORPORATION (US) 1981-04-14 — — US disclosed
EP-0028251-A4 PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER. ETHYL CORP (US) 1981-03-27 — — EP disclosed
WO-1980002421-A1 PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER ETHYL CORP (US) 1980-11-13 — — WO disclosed
US-4055663-A Halogenated acylamino acids as fungicides NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-10-25 — — US disclosed
US-4015008-A N,N-dichloro substituted aminocarboxylic acids as microbiocides NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-03-29 — — US disclosed
US-3950536-A N,N-Dichloro substituted aminocarboxylic acids as bactericides and fungicides BARER SOL JOSEPH 1976-04-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof CXCL10, MLX, MICA ALDH1A1 4840/4885HTT 3448/4885NCOA1 3048/4885
US-20100130416-A1 MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS VEGFA, APP, IAPP ALDH1A1 2501/4885HTT 109/4885NCOA1 4310/4885
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 ALDH1A1 4034/4885HTT 1830/4885NCOA1 3442/4885
US-20240183860-A1 Chimeric ABC Transporters and Screening Methods ABCB4, ABCE1, ABCD3 ALDH1A1 3456/4885HTT 1904/4885NCOA1 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.