SCHEMBL995228

SCHEMBL995228

O=C(CCl)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.64
▸ HTT P42858 1/20 0.64
▸ NCOA1 Q15788 1/20 0.64
▸ SMN1; SMN2 Q16637 1/20 0.64
▸ NCOA3 Q9Y6Q9 1/20 0.64
▸ MME P08473 3/20 0.59
▸ ACE P12821 7/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.58
▸ CTSG P08311 1/20 0.57
▸ CMA1 P23946 1/20 0.57
▸ FPR2 P25090 1/20 0.57
▸ NAALAD2 Q9Y3Q0 1/20 0.56
▸ ECE1 P42892 1/20 0.56
▸ LMNA P02545 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ CPA1 P15085 2/20 0.55
▸ ACE2 Q9BYF1 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293500 1.00 ALDH1A1 (0.64) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL995229 1.00 ALDH1A1 (0.64) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL23489727 0.87 ALDH1A1 (0.63) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL3510328 0.87 ACE (0.60) MMEACENAALAD2CPA1ACE2
SCHEMBL16892795 0.87 ACE (0.60) MMEACENAALAD2CPA1ACE2
SCHEMBL3510333 0.87 ACE (0.60) MMEACENAALAD2CPA1ACE2
SCHEMBL514883 0.87 ACE (0.62) MMEACENPSR1CTSGCMA1
SCHEMBL28952171 0.87 ACE (0.62) MMEACENPSR1CTSGCMA1
SCHEMBL29981912 0.86 FOLH1 (0.52) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3
SCHEMBL11503757 0.86 NOS2 (0.54) ALDH1A1HTTNCOA1SMN1; SMN2NCOA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240183860-A1 Chimeric ABC Transporters and Screening Methods GENENTECH, INC. (US) 2024-06-06 — — US claimed
EP-4330689-A2 CHIMERIC ABC TRANSPORTERS AND SCREENING METHODS Genentech, Inc. (US) 2024-03-06 — — EP claimed
CN-117203529-A Chimeric ABC transporter and screening method 基因泰克公司 2023-12-08 — — CN claimed
WO-2022232125-A2 CHIMERIC ABC TRANSPORTERS AND SCREENING METHODS GENENTECH, INC. (US) 2022-11-03 — — WO claimed
WO-2022104001-A1 EXPANDED PROTEIN LIBRARIES AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2022-05-19 — — WO claimed
US-20100130416-A1 MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS ARCHER PHARMACEUTICALS, INC. (US) 2010-05-27 — — US claimed
US-7629154-B2 Process for preparing highly optically pure L-amino acids, such as L-homophenylalanine (L-HPA) and the derivatives thereof, from N-protected amino acid by using the novel NAAAR combined with L-N-carbamoylase NATIONAL CHUNGHSING UNIVERSITY (TW) 2009-12-08 — — US claimed
WO-2009143489-A2 MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS ARCHER PHARMACEUTICALS, INC. (US) 2009-11-26 — — WO claimed
WO-2006092640-A1 ANTIPROLIFERATIVE PEPTIDES CONTAINING THE MOTIF PHE-TRP-LEU, PHARMACEUTICAL COMPOSITIONS AND MEDICAL USES THEREOF OROSZ ANTAL (HU) 2006-09-08 — — WO claimed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 — — EP disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 — — EP disclosed
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 — — US disclosed
EP-4722228-A1 NEW COMPOUND TARGETING MUSK AND USE THEREOF The University of Tokyo (JP) 2026-04-08 — — EP disclosed
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof GENEFRONTIER CORPORATION (JP) 2026-03-03 — — US disclosed
US-4262092-A Process for producing N-acyl-D-phenylalanine ester ETHYL CORPORATION (US) 1981-04-14 — — US disclosed
EP-0028251-A4 PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER. ETHYL CORP (US) 1981-03-27 — — EP disclosed
WO-1980002421-A1 PROCESS FOR PRODUCING N-ACYL-D-PHENYLALANINE ESTER ETHYL CORP (US) 1980-11-13 — — WO disclosed
US-4055663-A Halogenated acylamino acids as fungicides NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-10-25 — — US disclosed
US-4015008-A N,N-dichloro substituted aminocarboxylic acids as microbiocides NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1977-03-29 — — US disclosed
US-3950536-A N,N-Dichloro substituted aminocarboxylic acids as bactericides and fungicides BARER SOL JOSEPH 1976-04-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof CXCL10, MLX, MICA ALDH1A1 4840/4885HTT 3448/4885NCOA1 3048/4885
US-20100130416-A1 MODULATION OF ANGIOGENESIS BY A-BETA PEPTIDE FRAGMENTS VEGFA, APP, IAPP ALDH1A1 2501/4885HTT 109/4885NCOA1 4310/4885
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 ALDH1A1 4034/4885HTT 1830/4885NCOA1 3442/4885
US-20240183860-A1 Chimeric ABC Transporters and Screening Methods ABCB4, ABCE1, ABCD3 ALDH1A1 3456/4885HTT 1904/4885NCOA1 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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