Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A3GP6AGTR1AGTR2 | |
| SCHEMBL137 | 0.90 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9682924 | 0.90 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL409 | 0.88 | AGTR2 (0.57) | AGTR1AGTR2 | |
| SCHEMBL359 | 0.85 | GP6 (0.63) | GP6AGTR1AGTR2 | |
| SCHEMBL9683640 | 0.83 | GP6 (0.46) | SLC6A4SLC6A3GP6AGTR1AGTR2 | |
| SCHEMBL10587698 | 0.82 | AGTR1 (0.49) | GP6AGTR1AGTR2 | |
| SCHEMBL419 | 0.81 | SLC6A4 (0.46) | SLC6A4SLC6A3GP6AGTR1AGTR2 | |
| SCHEMBL417 | 0.81 | SLC6A4 (0.46) | SLC6A4SLC6A3GP6AGTR1AGTR2 | |
| SCHEMBL9684086 | 0.80 | SLC6A4 (0.46) | SLC6A4SLC6A3GP6AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128355-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-07 | — | — | US | disclosed |