Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 10/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 9/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590363 | 0.87 | AGTR1 (0.68) | AGTR2AGTR1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL18070889 | 0.76 | AGTR1 (0.56) | AGTR2AGTR1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL9591685 | 0.76 | AGTR1 (0.71) | AGTR2AGTR1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL6609133 | 0.71 | AGTR1 (0.58) | AGTR2AGTR1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL6605088 | 0.70 | AGTR1 (0.55) | AGTR2AGTR1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL3712006 | 0.70 | RPS6KB1 (0.63) | AGTR2AGTR1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL27391310 | 0.68 | CYP11B1 (0.41) | AGTR2AGTR1 | |
| SCHEMBL9386452 | 0.68 | NR2F2 (0.64) | AGTR2AGTR1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL5078942 | 0.66 | CFD (0.56) | AGTR2AGTR1ALDH1A1KDM4EUSP2 | |
| SCHEMBL27523674 | 0.66 | ADRA2A (0.39) | HSD17B10ALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475206-A2 | Angiotensin II receptor antagonists | ABBOTT LABORATORIES (US) | 1992-03-18 | — | — | EP | disclosed |