Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682970 | 0.83 | KMT2A (0.41) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL9027930 | 0.80 | L3MBTL1 (0.43) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL9684818 | 0.74 | CLCN2 (0.54) | CLCN2PTGS2MEN1KMT2AMAPT | |
| SCHEMBL9683792 | 0.73 | CLCN2 (0.52) | CLCN2PTGS2MEN1KMT2AMAPT | |
| SCHEMBL9683784 | 0.72 | CLCN2 (0.53) | CLCN2PTGS2MEN1KMT2AMAPT | |
| SCHEMBL14755496 | 0.72 | TASP1 (0.44) | PTGS2GAATHRBTSHRPTGS1 | |
| SCHEMBL8075141 | 0.71 | ADORA3 (0.50) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL7911040 | 0.70 | CLCN2 (0.59) | CLCN2PTGS2MEN1KMT2AMAPT | |
| SCHEMBL14755599 | 0.69 | GAA (0.48) | PTGS2MEN1KMT2AMAPTGAA | |
| SCHEMBL14755635 | 0.69 | ADORA3 (0.48) | MEN1KMT2AMAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114958-A | Lipoxygenase or cyclooxygenase inhibitors | WARNER-LAMBERT COMPANY (US) | 1992-05-19 | — | — | US | disclosed |