SCHEMBL8075141

SCHEMBL8075141

Cc1ccc(S(=O)(=O)c2nc(-c3ccccc3)ns2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
NR1H2 P55055 1/20 0.49
NR1H3 Q13133 1/20 0.49
ALDH1A1 P00352 7/20 0.48
NPSR1 Q6W5P4 2/20 0.47
MAPK1 P28482 2/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 1/20 0.45
HTT P42858 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
GAA P10253 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14755635 0.97 ADORA3 (0.48) ADORA3RXFP1NR1H2NR1H3ALDH1A1
SCHEMBL14755599 0.92 GAA (0.48) ADORA3RXFP1NR1H2NR1H3ALDH1A1
SCHEMBL7214866 0.89 ADORA3 (0.50) ADORA3ALDH1A1NPSR1MEN1KMT2A
SCHEMBL14755486 0.87 PTGS2 (0.49) GAA
SCHEMBL14755634 0.85 CTRC (0.44) RXFP1ALDH1A1NPSR1CYP1A2CYP2C9
SCHEMBL7513504 0.84 FAAH (0.42) ADORA3RXFP1ALDH1A1NPSR1KMT2A
SCHEMBL14755802 0.84 BCHE (0.45) ADORA3RXFP1ALDH1A1NPSR1HPGD
SCHEMBL14755809 0.83 MAPT (0.51) ADORA3ALDH1A1NPSR1MAPK1MEN1
SCHEMBL14755759 0.82 BCHE (0.45) ALDH1A1NPSR1KMT2AKDM4EMAPT
SCHEMBL9027930 0.82 L3MBTL1 (0.43) RXFP1ALDH1A1NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0842146-B1 OXIMETHER AND ACRYLIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER AG (DE) 2000-08-23 EP disclosed
US-5977123-A Oximether and acrylic acid derivatives and their use as fungicides BAYER AKTIENGESELLSCGAFT (DE) 1999-11-02 US disclosed