Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683493 | 0.82 | MEN1 (0.59) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9681871 | 0.80 | MAPT (0.43) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9681343 | 0.80 | HDAC3 (0.44) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9683331 | 0.79 | MAP2K4 (0.52) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL12658350 | 0.77 | SHMT2 (0.48) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9681404 | 0.77 | MAPT (0.56) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11935975 | 0.76 | SHMT2 (0.57) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22384733 | 0.75 | HDAC1 (0.64) | MEN1KMT2ASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9683458 | 0.75 | SSTR3 (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5923871 | 0.74 | MEN1 (0.72) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |