Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.45 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016390 | 0.91 | MEN1 (0.56) | MAP2K4MEN1KMT2AGPR35NCF1 | |
| SCHEMBL9683167 | 0.82 | HTT (0.51) | MEN1KMT2ANCF1GAAMAPT | |
| SCHEMBL9681343 | 0.80 | HDAC3 (0.44) | MEN1KMT2AGAAMAPTRAB9A | |
| SCHEMBL9681871 | 0.80 | MAPT (0.43) | MEN1KMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL7740760 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2AGAAMAPTNPC1 | |
| SCHEMBL9682485 | 0.79 | GAA (0.51) | MEN1KMT2ANCF1GAAMAPT | |
| SCHEMBL9682993 | 0.79 | MEN1 (0.47) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL21382629 | 0.79 | PDE5A (0.53) | MEN1KMT2ANCF1GAAMAPT | |
| SCHEMBL24636068 | 0.79 | MAPT (0.59) | MEN1KMT2ANCF1GAAMAPT | |
| SCHEMBL8405018 | 0.78 | HDAC1 (0.62) | MEN1KMT2ANCF1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |