Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190896 | 0.81 | THRB (0.35) | THRATHRBTDP1MAPK1ALDH1A1 | |
| SCHEMBL9685152 | 0.75 | SCN4A (0.34) | TDP1ALDH1A1GAAMAOA | |
| SCHEMBL26230974 | 0.69 | MCL1 (0.54) | TDP1MAPK1ALDH1A1HTTGAA | |
| SCHEMBL9683985 | 0.68 | NPC1 (0.44) | THRATHRBCA12CA1CA2 | |
| SCHEMBL29371701 | 0.68 | TDP1 (0.47) | THRATHRBTDP1MAPK1ALDH1A1 | |
| SCHEMBL18071648 | 0.67 | GPR84 (0.43) | TDP1MAPK1ALDH1A1EPHX2HTT | |
| SCHEMBL8633464 | 0.67 | ALDH1A1 (0.37) | MAPK1ALDH1A1GAA | |
| SCHEMBL9142141 | 0.67 | — | — | |
| SCHEMBL16903841 | 0.67 | TDP1 (0.66) | TDP1MAPK1EPHX2HTTGAA | |
| SCHEMBL18997834 | 0.67 | SCN4A (0.55) | TDP1ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106522-A | Liquid hydrophobic vehicle for electro-rheological fluid | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-04-21 | — | — | US | claimed |
| EP-0150994-B1 | ELECTRO-RHEOLOGICAL FLUID COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-11-19 | — | — | EP | claimed |
| EP-0150994-A1 | Electro-rheological fluid compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-08-07 | — | — | EP | claimed |
| US-5106522-A | Liquid hydrophobic vehicle for electro-rheological fluid | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-04-21 | — | — | US | disclosed |
| EP-0150994-B1 | ELECTRO-RHEOLOGICAL FLUID COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-11-19 | — | — | EP | disclosed |
| EP-0150994-A1 | Electro-rheological fluid compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-08-07 | — | — | EP | disclosed |