Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591657 | 0.88 | SMN1; SMN2 (0.75) | SMN1; SMN2MAPTKDM4ECYP1A2CYP2D6 | |
| SCHEMBL11543260 | 0.86 | EIF4A1 (0.55) | SMN1; SMN2LTB4R2FFAR1AKR1C2LPAR1 | |
| SCHEMBL4911849 | 0.85 | PPARA (0.59) | SMN1; SMN2MAPTLTB4R2ALDH1A1LPAR1 | |
| SCHEMBL9511283 | 0.85 | LTB4R (0.53) | SMN1; SMN2KDM4ELTB4R2LTB4RRAB9A | |
| SCHEMBL20594609 | 0.84 | RAB9A (0.54) | SMN1; SMN2LTB4R2RAB9AALDH1A1 | |
| SCHEMBL9514041 | 0.83 | PTGER4 (0.46) | SMN1; SMN2MAPTTP53LMNARAB9A | |
| SCHEMBL8566031 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9151080 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9683222 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTLMNAKDM4ECYP1A2 | |
| SCHEMBL6701301 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAKDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805134-B1 | NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2000-08-30 | — | — | EP | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| EP-0805134-A1 | NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5653911-A | Liquid crystalline compound liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1997-08-05 | — | — | US | disclosed |