Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682485 | 0.91 | GAA (0.51) | HTTACP1NCF1BCHEACHE | |
| SCHEMBL9683129 | 0.86 | MAPT (0.47) | MAPTRAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL9683331 | 0.82 | MAP2K4 (0.52) | NCF1MAPTNPC1LMNARAB9A | |
| SCHEMBL13186988 | 0.82 | ACP1 (0.49) | HTTACP1NCF1BCHEACHE | |
| SCHEMBL23641246 | 0.82 | MAPT (0.48) | HTTBCHEACHEMAPTMEN1 | |
| SCHEMBL4308882 | 0.81 | ABL1 (0.51) | CNR1MAPTNPC1LMNARAB9A | |
| SCHEMBL11569274 | 0.80 | ALDH1A1 (0.49) | MAPTRAB9AL3MBTL1VNN1GAA | |
| SCHEMBL9682901 | 0.80 | MAPT (0.43) | MAPTNPC1RAB9AL3MBTL1GAA | |
| SCHEMBL11274390 | 0.80 | PKM (0.52) | MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL9683493 | 0.79 | MEN1 (0.59) | HTTMAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |