Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 3/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674454 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAHTTCRHBP | |
| SCHEMBL16701556 | 0.79 | ALDH1A1 (0.70) | ALDH1A1HTTCRHBPCRHR2MEN1 | |
| SCHEMBL129460 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAHTTCRHBP | |
| SCHEMBL566881 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CRHBPCRHR2MEN1KMT2A | |
| SCHEMBL946547 | 0.78 | TSHR (0.53) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL5073938 | 0.77 | SMN1; SMN2 (0.50) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL7116822 | 0.77 | TSHR (0.49) | MEN1KMT2ATSHR | |
| SCHEMBL599831 | 0.76 | CRHBP (0.63) | ALDH1A1KDM4ELMNAHTTCRHBP | |
| SCHEMBL3154735 | 0.76 | CRHBP (0.55) | ALDH1A1LMNACRHBPCRHR2MEN1 | |
| SCHEMBL876446 | 0.76 | MAPT (0.57) | ALDH1A1KDM4ELMNAHTTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169844-A | Enzyme inhibitor, anticholesterol and antilipemic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |