SCHEMBL9683662

SCHEMBL9683662

O=C(O)CCNC(=O)C(Cc1ccc(-c2ccc(Cl)cc2)cc1)NCP(=O)(O)O

nearest known ligand 0.74

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MMEL1 Q495T6 1/20 0.54
MME P08473 3/20 0.46
ACE P12821 1/20 0.46
ECE1 P42892 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL489231 0.92 MMEL1 (0.64) MMEL1MMEACEECE1
SCHEMBL489232 0.92 MMEL1 (0.64) MMEL1MMEACEECE1
Bromide SCHEMBL9683926 0.91 MMEL1 (0.62) MMEL1MMEACEECE1
SCHEMBL9682406 0.89 MMEL1 (0.54) MMEL1MMEACEECE1
SCHEMBL7343519 0.89 MMEL1 (0.54) MMEL1MMEACEECE1
SCHEMBL7313027 0.86 MMEL1 (0.52) MMEL1
SCHEMBL7316768 0.85 MMEL1 (0.55) MMEL1MMEACEECE1
SCHEMBL7309965 0.84 MMEL1 (0.53) MMEL1
SCHEMBL7310571 0.83 MMEL1 (0.53) MMEL1MMEACEECE1
SCHEMBL7338163 0.82 MMEL1 (0.49) MMEL1MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511940-A2 Phosphono/biaryl substituted dipeptide derivatives CIBA-GEIGY AG (CH) 1992-11-04 EP claimed
EP-0511940-A2 Phosphono/biaryl substituted dipeptide derivatives CIBA-GEIGY AG (CH) 1992-11-04 EP disclosed