Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316768 | 0.95 | MMEL1 (0.55) | MMEL1MMEACEECE1 | |
| SCHEMBL489231 | 0.91 | MMEL1 (0.64) | MMEL1MMEACEECE1 | |
| SCHEMBL489232 | 0.91 | MMEL1 (0.64) | MMEL1MMEACEECE1 | |
| Bromide SCHEMBL9683926 | 0.90 | MMEL1 (0.62) | MMEL1MMEACEECE1 | |
| SCHEMBL7320399 | 0.88 | MMEL1 (0.47) | MMEL1 | |
| SCHEMBL7320009 | 0.86 | MMEL1 (0.48) | MMEL1 | |
| SCHEMBL7320404 | 0.84 | MMEL1 (0.50) | MMEL1 | |
| SCHEMBL15202503 | 0.84 | L3MBTL1 (0.63) | MMEL1MMEACEECE1 | |
| SCHEMBL7319125 | 0.83 | MME (0.55) | MMEACEECE1 | |
| SCHEMBL9683662 | 0.83 | MMEL1 (0.54) | MMEL1MMEACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |