Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CBX7 | O95931 | 4/20 | 0.49 |
| ▸ | CDYL2 | Q8N8U2 | 4/20 | 0.49 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.49 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683762 | 0.78 | ALDH1A1 (0.76) | ALDH1A1HPGDTP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL8700563 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDTP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL9683737 | 0.75 | ALDH1A1 (0.70) | ALDH1A1HPGDTP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL5171751 | 0.72 | ALDH1A1 (0.68) | ALDH1A1HPGDTP53SMN1; SMN2POLB | |
| SCHEMBL474056 | 0.72 | ALDH1A1 (0.73) | ALDH1A1HPGDTP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL15426204 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HPGDTP53SIGMAR1POLB | |
| SCHEMBL14565048 | 0.71 | ALDH1A1 (0.77) | ALDH1A1HPGDTP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL9682902 | 0.71 | ALDH1A1 (0.67) | ALDH1A1HPGDTP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL15435589 | 0.71 | GPR84 (0.65) | ALDH1A1TP53SMN1; SMN2NPSR1GPR84 | |
| SCHEMBL2980233 | 0.70 | SMN1; SMN2 (0.71) | ALDH1A1HPGDTP53SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |