Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450761 | 0.77 | HTR1A (0.41) | KDM4EHTR1ASLC6A2FPR2PROKR1 | |
| SCHEMBL9450885 | 0.76 | HTR1A (0.43) | ALDH1A1KDM4EHTR1ASLC6A2SLC6A4 | |
| SCHEMBL6123500 | 0.76 | SCD (0.51) | ALDH1A1SLC6A2NOTUMPRKAB2PRKAG1 | |
| SCHEMBL9450786 | 0.74 | SCN9A (0.41) | HTR1ASLC6A2MEN1KMT2A | |
| SCHEMBL9450889 | 0.74 | KIF11 (0.40) | KDM4EKIF11HTR1ASLC6A2 | |
| SCHEMBL9683909 | 0.72 | SLC6A4 (0.40) | ALDH1A1KDM4EKIF11HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL9682487 | 0.71 | SLC6A4 (0.39) | ALDH1A1KDM4EKIF11HTR1ASLC6A2 | |
| SCHEMBL27037992 | 0.71 | PRKAB2 (0.47) | GRM5PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1196749 | 0.71 | PRKAB2 (0.47) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL6123546 | 0.71 | EPHX2 (0.40) | MEN1KMT2AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |