Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683933 | 0.98 | MAPT (0.54) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL9684734 | 0.76 | RAB9A (0.51) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL28013888 | 0.75 | HTT (0.62) | MAPTSMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL9684489 | 0.74 | PTPRC (0.49) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL11116815 | 0.72 | MEN1 (0.72) | MAPTRAB9AALDH1A1LMNAHTT | |
| SCHEMBL9685931 | 0.71 | PTPRC (0.47) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL9385816 | 0.71 | ALDH1A1 (0.66) | MAPTSMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL9385826 | 0.71 | ALDH1A1 (0.66) | MAPTSMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL8141752 | 0.70 | HTT (0.68) | MAPTSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL6771599 | 0.70 | ALDH1A1 (0.64) | MAPTSMN1; SMN2RAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |